About 11 results found for searched term "K 114" (0.258 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2060 | SC-514 | IκB/IKK |
| GK 01140 | ||
| SC-514 is a selective and reversible inhibitor of IκB kinase 2 (IKK2) with IC50 of 3-12 μM. | ||
| M6861 | K 114 | Others |
| K 114 is a amyloid fibril-specific fluorescent dye. | ||
| M9281 | KIN1148 | Adjuvants |
| KIN-1148 | ||
| KIN1148 is a IRF3 agonist, it is also a novel influenza vaccine adjuvant found to enhance flu vaccine efficacy. | ||
| M25103 | Ansuvimab | Anti-infection |
| zz-zyk mAb114 | ||
| Ansuvimab (Ansuvimab-zyk) is a recombinant human monoclonal IgG1 antibody that exhibits antiviral activity against Zaire ebolavirus. Ansuvimab binds to the glycoprotein on Zaire ebolavirus to block its entry into host cells. | ||
| M10637 | GSK3368715 2HCl | PRMTs |
| EPZ019997 2HCl | ||
| GSK3368715 2HCl is a novel potent, orally active, reversible type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50 values of 3.1 nM, 48 nM, 1148 nM, 5.7 nM and 1.7 nM for PRMT1, PRMT3, PRMT4, PRMT6, PRMT8, respectively. | ||
| M11405 | Inavolisib (GDC-0077) | PI3K |
| GDC-0077; RG6114；RO-7113755 | ||
| Inavolisib (GDC-0077; RG6114) is a potential best-in-class, orally selective PI3Kα inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114) is more selective for mutants compared to wild-type PI3Kα. It can trigger the degradation of mutation-producing PIK3α. | ||
| M13596 | Atuveciclib | CDK |
| BAY-1143572 | ||
| Atuveciclib (BAY-1143572) is a potent and highly selective, oral PTEFb/CDK9 inhibitor. Atuveciclib (BAY-1143572) inhibits CDK9/CycT1 with an IC50 of 13 nM. | ||
| M19986 | Recombinant Human CXCL6 (Mammalian, C-6His) | Recombinant Proteins |
| C-X-C Motif Chemokine 6; Chemokine Alpha 3 | ||
| The recombinant human C-X-C Motif Chemokine 6 was generated by the mammalian expression system and the target gene encoding Gly38-ASN114 was expressed with a 6His marker at the C-terminus. Protein number: P80162. | ||
| M21471 | Recombinant Human Transferrin (Mammalian, C-6His) | Recombinant Proteins |
| Serotransferrin; Transferrin; Beta-1 metal-binding globulin | ||
| Recombinant human transferrin is produced by mammalian expression system, and the target gene is encoded as Val20-Pro698, which is expressed by 6His marker at the C-terminal. Protein number: AAA61140.1. | ||
| M28726 | GSK3368715 | Histone Methyltransferase |
| EPZ019997 | ||
| GSK3368715 (EPZ019997) is an orally active, reversible, and S-adenosyl-L-methionine (SAM) uncompetitive type I protein arginine methyltransferases (PRMTs) inhibitor (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8)). GSK3368715 (EPZ019997) produces a shift in arginine methylation states, alters exon usage, and has strong anti-cancer activity. | ||
| M49565 | Ilunocitinib | JAK |
| Ilunocitinib is a JAK inhibitor (extracted from patent WO2009114512A1). | ||
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